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Novel Fluorescent Probe for Low Density Lipoprotein, Based on the Enhancement of Europium Emission Band

Novel Fluorescent Probe for Low Density Lipoprotein, Based on the Enhancement of Europium Emission Band

L C Courrol, A M Monteiro, F R O Silva, L Gomes, N D Vieira Jr, M A Gidlund, A M Figueiredo Neto

Opt Express. 2007 May 28;15(11):7066-74.

PMID: 19547024

Abstract:

We report here the observation of the enhancement of Europium-tetracycline complex emission in Low Density Lipoprotein (LDL) solutions. Europium emission band of tetracycline solution containing Europium (III) chloride hexahydrate was tested to obtain effective enhancement in the presence of native LDL and oxidized LDL. Europium emission lifetime in the presence of lipoproteins was measured, resulting in a simple method to measure the lipoproteins quantity in an aqueous solution at physiological pH. This method shows that the complex can be used as a sensor to determine the different states of native and oxidized LDL in biological fluids.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP13759927	Europium(III) chloride hexahydrate		13759-92-7	Price

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