Home
Resources
Publications
Novel Magnetic Cross-Linked Lipase Aggregates for Improving the Resolution of (R, S)-2-octanol

Novel Magnetic Cross-Linked Lipase Aggregates for Improving the Resolution of (R, S)-2-octanol

Ying Liu, Chen Guo, Chun-Zhao Liu

Chirality. 2015 Mar;27(3):199-204.

PMID: 25482205

Abstract:

Novel magnetic cross-linked lipase aggregates were fabricated by immobilizing the cross-linked lipase aggregates onto magnetic particles with a high number of -NH2 terminal groups using p-benzoquinone as the cross-linking agent. At the optimal fabrication conditions, 100% of immobilization efficiency and 139% of activity recovery of the magnetic cross-linked lipase aggregates were achieved. The magnetic cross-linked lipase aggregates were able to efficiently resolve (R, S)-2-octanol, and retained 100% activity and 100% enantioselectivity after 10 cycles of reuse, whereas the cross-linked lipase aggregates only retained about 50% activity and 70% enantioselectivity due to insufficient cross-linking. These results provide a great potential for industrial applications of the magnetic cross-linked lipase aggregates.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP5978701	(R)-(−)-2-Octanol		5978-70-1	Price

As a specialist in analytical chemical Products, Alfa Chemistry offers consumers a wealth of raw materials and a full range of technologies and services.

QUICK LINKS

HEADQUARTERS

Tel:

Fax:

Email: