Home
Resources
Publications
Oral Lipase Activities and Fat-Taste Receptors for Fat-Taste Sensing in Chickens

Oral Lipase Activities and Fat-Taste Receptors for Fat-Taste Sensing in Chickens

Yuko Kawabata, Fuminori Kawabata, Shotaro Nishimura, Shoji Tabata

Biochem Biophys Res Commun. 2018 Jan 1;495(1):131-135.

PMID: 29080746

Abstract:

It has been reported that a functional fat-taste receptor, GPR120, is present in chicken oral tissues, and that chickens can detect fat taste in a behavioral test. However, although triglycerides need to be digested to free fatty acids to be recognized by fat-taste receptors such as GPR120, it remains unknown whether lipase activities exist in chicken oral tissues. To examine this question, we first cloned another fat-taste receptor candidate gene, CD36, from the chicken palate. Then, using RT-PCR, we determined that GPR120 and CD36 were broadly expressed in chicken oral and gastrointestinal tissues. Also by RT-PCR, we confirmed that several lipase genes were expressed in both oral and gastrointestinal tissues. Finally, we analyzed the lipase activities of oral tissues by using a fluorogenic triglyceride analog as a lipase substrate. We found there are functional lipases in oral tissues as well as in the stomach and pancreas. These results suggested that chickens have a basic fat-taste reception system that incorporates a triglycerides/oral-lipases/free fatty acids/GPR120 axis and CD36 axis.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP195833466	Lipase Substrate		195833-46-6	Price

As a specialist in analytical chemical Products, Alfa Chemistry offers consumers a wealth of raw materials and a full range of technologies and services.

QUICK LINKS

HEADQUARTERS

Tel:

Fax:

Email: