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Ortho-directed Functionalization of Arenes Using Magnesate Bases

Estelle Bellamy, Omar Bayh, Christophe Hoarau, Francois Trécourt, Guy Quéguiner, Francis Marsais

Chem Commun (Camb). 2010 Oct 7;46(37):7043-5.

PMID: 20798902

Abstract:

Ortho-directed functionalisation of arenes using lithium alkylmagnesate bases were achieved, demonstrating the potential use of arylmagnesates as suitable arylanions, without a further transmetallation step, for challenging functionalizations such as fluorination, hydroxylation, arylation, vinylation and alkylation through epoxide ring-opening.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP20910207 Tri-n-butyllithium magnesate Tri-n-butyllithium magnesate 20910-20-7 Price
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