Home
Resources
Publications
Parkinsonism Relating to Intoxication With Glyphosate

Parkinsonism Relating to Intoxication With Glyphosate

Makoto Eriguchi, Kotaro Iida, Shuhei Ikeda, Manabu Osoegawa, Kenya Nishioka, Nobutaka Hattori, Hiroshi Nagayama, Hideo Hara

Intern Med. 2019 Jul 1;58(13):1935-1938.

PMID: 30799335

Abstract:

We herein report the case of a 38-year-old man who developed parkinsonism 4 years after ingesting glyphosate. The patient presented with right-sided bradykinesia and cogwheel rigidity without autonomic symptoms. Magnetic resonance imaging of the brain and [123I]-metaiodobenzylguanidine myocardial scintigraphy were normal. A drastic response to levodopa and the presence of levodopa-induced dyskinesia without strong non-motor symptoms were seen in this patient. We considered that young-onset atypical parkinsonism was associated with a history of sublethal glyphosate ingestion. Epidemiologic investigations have shown that exposure to pesticides is a risk factor for Parkinson's disease (PD). Our findings support the notion that glyphosate exposure might be related to the onset of PD.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AS2121361	Herbicides I			Price

As a specialist in analytical chemical Products, Alfa Chemistry offers consumers a wealth of raw materials and a full range of technologies and services.

QUICK LINKS

HEADQUARTERS

Tel:

Fax:

Email: