Parsley

PMID: 30000940

Abstract:

Parsley (Carum petroselinum) leaf, seed, and root contain the volatile oils apiol and myristicin, which is pharmacologically active, as well as flavonoids, beta-phellandrene; bergapten; and vitamins A and C. Warm compresses or poultices of parsley have been used to treat breast engorgement and mastalgia[1][2] Oral capsules containing sage and parsley capsules are said to decrease milk flow; however, no scientifically valid clinical trials support this use. Galactogogues should never replace evaluation and counseling on modifiable factors that affect milk production.[3] No data exist on the excretion of any components of parsley into breastmilk or on the safety and efficacy of parsley nursing mothers or infants. Parsley is "generally recognized as safe" (GRAS) as a food by the U.S. Food and Drug Administration. Adverse reactions are primarily allergic, including cross reactions to other members of the Apiaceae family, such as carrot, celery, and fennel. The essential oil should not be used because of potential toxicity of its apiol and myristicin content.
Dietary supplements do not require extensive pre-marketing approval from the U.S. Food and Drug Administration. Manufacturers are responsible to ensure the safety, but do not need to prove the safety and effectiveness of dietary supplements before they are marketed. Dietary supplements may contain multiple ingredients, and differences are often found between labeled and actual ingredients or their amounts. A manufacturer may contract with an independent organization to verify the quality of a product or its ingredients, but that does not certify the safety or effectiveness of a product. Because of the above issues, clinical testing results on one product may not be applicable to other products. More detailed information about dietary supplements is available elsewhere on the LactMed Web site.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP484208-A	Bergapten		484-20-8	Price

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