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Pentoxifylline and Nephroprotection: Effects on Renal Dysfunction and Cardiovascular Risks

Pentoxifylline and Nephroprotection: Effects on Renal Dysfunction and Cardiovascular Risks

I T Murkamilov, K A Aitbaev, V V Fomin, Zh A Murkamilova, A A Bayzhigitova

Ter Arkh. 2019 Mar 11;91(1):95-100.

PMID: 31090379

Abstract:

Generalized data on nephroprotective efficacy of pentoxifylline in chronic kidney disease (CKD) are presented. The potential of this drug in treating people suffering from CKD and cardiovascular diseases (CVD) with a high risk of developing the terminal stage of renal dysfunction is considered. Antiproteinuric, antifibrotic and anti-inflammatory effects of pentoxifylline significantly reduce the risk of progression of CKD and joining of CVD in the future. Efficacy in preventing the onset of the uremic stage of CKD, safety andapplicability at all stages of renal dysfunction development make pentoxifylline a very appealing drug not only for nephrologists but also for physicians. Keywords: chronic kidney disease, progression, pentoxifylline, nephroprotection, cardiovascular diseases.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP6493056-A	Pentoxifylline		6493-05-6	Price

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