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Perindopril and Ramipril Phosphonate Analogues as a New Class of Angiotensin Converting Enzyme Inhibitors

Catherine Gomez, Sabine Berteina-Raboin, Guillaume De Nanteuil, Gérald Guillaumet

Bioorg Med Chem. 2013 Nov 15;21(22):7216-21.

PMID: 24095015

Abstract:

A series of phosphonate analogues related to perindopril and ramipril were prepared and tested to estimate their ability to inhibit angiotensin converting enzyme. These new synthesized compounds were active ACE inhibitors with a promising activity.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP130061288 Perindopril Related Compound D Perindopril Related Compound D 130061-28-8 Price
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