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Phase Equilibria of the Ternary System 1-palmitoyl-sn-glycero-3-phosphocholine/oleic acid/water Studied by NMR

I Brentel, G Arvidson, G Lindblom

Biochim Biophys Acta. 1987 Nov 13;904(2):401-4.

PMID: 3663679

Abstract:

Part of a phase diagram for the system 1-palmitoyl-sn-glycero-3-phosphocholine (PamGroPCho)/oleic acid/water has been constructed from mainly 31P-NMR data and a previous determination of the phase equilibria of the binary PamGroPCHo/water system. It was found that the appearance of the phase diagram is very similar to those found for several simple soap/fatty acid/water or soap/long-chain alcohol/water systems. The most striking features observed are: (1) the lamellar phase can swell towards very high water contents (2) vesicles are formed after sonication and (3) the cubic liquid crystalline phase disappears upon addition of very small amounts of oleic acid. The self-association of the amphiphiles and the shape of the aggregates are discussed in terms of existing first-order approximative theories.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP17364168 1-Palmitoyl-sn-glycero-3-phosphocholine 1-Palmitoyl-sn-glycero-3-phosphocholine 17364-16-8 Price
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