Home
Resources
Publications
Phosphate-selective Fluorescent Sensing Microspheres Based on Uranyl Salophene Ionophores

Phosphate-selective Fluorescent Sensing Microspheres Based on Uranyl Salophene Ionophores

Katarzyna Wygladacz, Yu Qin, Wojciech Wroblewski, Eric Bakker

Anal Chim Acta. 2008 Apr 28;614(1):77-84.

PMID: 18405684

Abstract:

Optical dihydrogen phosphate-selective sensors that function on the basis of bulk optode principles and are based on two different uranyl salophene ionophores are reported here for the first time. The influence of the optode composition and measuring conditions such as sample pH on the optode response are characterized, along with sensor selectivity and long-term stability. Three plasticizers of different polarity are considered for optode fabrication: bis(2-ethylhexyl)sebacate (DOS), dodecyl 2-nitrophenyl ether (o-NPDDE), o-nitrophenyloctylether (o-NPOE). The compounds 9-(diethylamino)-5-(octadecanoylimino)-5H-benzo[a]phenoxazine (ETH 5294, chromoionophore I) and 9-(diethylamino)-5-[(2-octyldecyl)imino]benzo[a]phenoxazine (ETH 5350, chromoionophore III) are used as H(+)-selective fluoroionophores that also act as reference ionophores. The resulting optode-based sensors are compared with their ion-selective electrode (ISE) counterparts, and it is revealed that optodes are better suited for operation at physiological pH. The best optode performance was found for the two component optode sensors doped with ETH 5350 and phosphate ionophore(I). The linear range of these sensor was loga=-6.0 to -2.6. Dihydrogen phosphate-selective optode sensors of optimized composition are fabricated in microsphere format and preliminary measurements in diluted sheep blood samples are presented.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP83027718	Dodecyl 2-nitrophenyl ether		83027-71-8	Price

As a specialist in analytical chemical Products, Alfa Chemistry offers consumers a wealth of raw materials and a full range of technologies and services.

QUICK LINKS

HEADQUARTERS

Tel:

Fax:

Email: