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Phosphonoacetic Acid in the Treatment of Experimental Herpes Simplex Keratitis

D D Gerstein, C R Dawson, J O O

Antimicrob Agents Chemother. 1975 Mar;7(3):285-8.

PMID: 1137379

Abstract:

In a rabbit model of herpes simplex corneal ulceration, 5% phosphonoacetic acid solution or ophthalmic ointment suppressed clinical disease and virus replication. The effect of 5% phosphonoacetic acid ointment was equivalent to that of 0.5% idoxuridine ointment in the treatment of this established herpetic eye infection.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP4408780-A Phosphonoacetic acid solution Phosphonoacetic acid solution 4408-78-0 Price
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