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Photoinduced Deaminative Borylation of Alkylamines

Jingjing Wu, Lin He, Adam Noble, Varinder K Aggarwal

J Am Chem Soc. 2018 Aug 29;140(34):10700-10704.

PMID: 30091912

Abstract:

An operationally simple deaminative borylation reaction of primary alkylamines has been developed. The formation of electron-donor-acceptor complexes between N-alkylpyridinium salts and bis(catecholato)diboron enables photoinduced single-electron transfer and fragmentation to carbon-centered radicals, which are subsequently borylated. The mild conditions allow a diverse range of readily available alkylamines to be efficiently converted into synthetically valuable alkylboronic esters under catalyst-free conditions.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP13826272 Bis(catecholato)diboron Bis(catecholato)diboron 13826-27-2 Price
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