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Plugging gp120s Cavity

Alexander Repik, Paul R Clapham

Structure. 2008 Nov 12;16(11):1603-4.

PMID: 19000812

Abstract:

NBD-556 is a class of HIV-1 entry inhibitors that binds HIV-1 surface glycoprotein gp120 and induces conformational changes, which mimic those caused by CD4 binding. Here, Madani et al. (2008) show that NBD-556 binds to the highly conserved "Phe-43 cavity" on gp120.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP333353449 NBD-556 NBD-556 333353-44-9 Price
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