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Poly(3,4-ethylenedioxythiophene) (PEDOT) Derivatives: Innovative Conductive Polymers for Bioelectronics

Daniele Mantione, Isabel Del Agua, Ana Sanchez-Sanchez, David Mecerreyes

Polymers (Basel). 2017 Aug 11;9(8):354.

PMID: 30971030

Abstract:

Poly(3,4-ethylenedioxythiophene)s are the conducting polymers (CP) with the biggest prospects in the field of bioelectronics due to their combination of characteristics (conductivity, stability, transparency and biocompatibility). The gold standard material is the commercially available poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS). However, in order to well connect the two fields of biology and electronics, PEDOT:PSS presents some limitations associated with its low (bio)functionality. In this review, we provide an insight into the synthesis and applications of innovative poly(ethylenedioxythiophene)-type materials for bioelectronics. First, we present a detailed analysis of the different synthetic routes to (bio)functional dioxythiophene monomer/polymer derivatives. Second, we focus on the preparation of PEDOT dispersions using different biopolymers and biomolecules as dopants and stabilizers. To finish, we review the applications of innovative PEDOT-type materials such as biocompatible conducting polymer layers, conducting hydrogels, biosensors, selective detachment of cells, scaffolds for tissue engineering, electrodes for electrophysiology, implantable electrodes, stimulation of neuronal cells or pan-bio electronics.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP126213501 3,4-Ethylenedioxythiophene 3,4-Ethylenedioxythiophene 126213-50-1 Price
AP126213512 Poly(3,4-ethylenedioxythiophene) Poly(3,4-ethylenedioxythiophene) 126213-51-2 Price
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