Home
Resources
Publications
Poly(N-acryloyl-glucosamine-co-methylenebisacrylamide)-based Hydrophilic Magnetic Nanoparticles for the Extraction of Aminoglycosides in Meat Samples

Poly(N-acryloyl-glucosamine-co-methylenebisacrylamide)-based Hydrophilic Magnetic Nanoparticles for the Extraction of Aminoglycosides in Meat Samples

Huiying Liu, Nan Li, Xuebo Liu, Yongzhong Qian, Jing Qiu, Xiaoning Wang

J Chromatogr A. 2020 Jan 4;1609:460517.

PMID: 31521380

Abstract:

Poly(N-acryloyl-glucosamine-co-methylenebisacrylamide) (poly(AGA-co-MBA))-modified Fe3O4 nanoparticles were prepared via simple aqueous surface polymerization. The resultant Fe3O4@poly(AGA-co-MBA) nanoparticles were used as hydrophilic magnetic solid phase extraction sorbents. Ten aminoglycosides were selected as model analytes to evaluate the extraction performance and mechanism of the sorbents. The prepared magnetic nanoparticles were characterized by Fourier transformed infrared spectroscopy, elemental analysis, a vibrating sample magnetometer, and so on. The sorbents exhibited efficient extraction towards model analytes in hydrophilic interaction chromatography. Only 10.0 mg of sorbent was needed to adsorb analytes from 10.0 mL of a sample solution within a short time (5.0 min). Under optimized conditions, Fe3O4@poly(AGA-co-MBA) nanoparticles were applied in the sample preparation for the analysis of 10 aminoglycosides in meat samples by high-performance liquid chromatography-tandem mass spectrometry. The limits of detection (LODs) for the 10 aminoglycosides were in the range of 0.6-23.6 µg kg-1. Satisfactory recoveries of spiked meat samples from 84.6-98.3% with acceptable relative standard deviations from 3.1% to 7.8% were achieved. Compared to other reported methods for the analysis of aminoglycosides, the present work had comparable or higher sensitivities with a simple extraction procedure. The proposed hydrophilic interaction extraction sorbents are promising as powerful alternatives for extracting and enriching aminoglycosides in animal-derived food samples.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP110269	N,N′-Methylenebisacrylamide solution		110-26-9	Price

As a specialist in analytical chemical Products, Alfa Chemistry offers consumers a wealth of raw materials and a full range of technologies and services.

QUICK LINKS

HEADQUARTERS

Tel:

Fax:

Email: