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Poly(N-isopropylacrylamide) Phase Diagrams: Fifty Years of Research

Poly(N-isopropylacrylamide) Phase Diagrams: Fifty Years of Research

Avraham Halperin, Martin Kröger, Françoise M Winnik

Angew Chem Int Ed Engl. 2015 Dec 14;54(51):15342-67.

PMID: 26612195

Abstract:

In 1968, Heskins and Guillet published the first systematic study of the phase diagram of poly(N-isopropylacrylamide) (PNIPAM), at the time a "young polymer" first synthesized in 1956. Since then, PNIPAM became the leading member of the growing families of thermoresponsive polymers and of stimuli-responsive, "smart" polymers in general. Its thermal response is unanimously attributed to its phase behavior. Yet, in spite of 50 years of research, a coherent quantitative picture remains elusive. In this Review we survey the reported phase diagrams, discuss the differences and comment on theoretical ideas regarding their possible origins. We aim to alert the PNIPAM community to open questions in this reputably mature domain.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
LS74686	Poly(N-isopropylacrylamide)			Price

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