0

Polymeric Disinfectant Nanocapsules: Effect of Molecular Weight of Poly(methyl Acrylate)

Saovaree Tanpantree, Pakorn Opaprakasit, Duangporn Polpanich, Srung Smanmoo, Pramuan Tangboriboonrat

J Biomed Nanotechnol. 2010 Aug;6(4):385-90.

PMID: 21323112

Abstract:

Poly(methyl acrylate) (PMA) of various weight average molecular weights (Mw) were synthesized via the iniferter route and applied for the encapsulation of disinfectant agent (chlorhexidine digluconate; CHD) by using the controlled precipitation technique. The encapsulation efficiency of CHD-PMA nanocapsules suspended in cyclohexane increased from 70 to 100% when the Mw of PMA increased from 40 K to 550 K. After redispersing the capsules into 0.5% w/v of sodium dodecyl sulphate aqueous solution, the maximum content of CHD in the nanocapsules remained >90%. Transmission electron micrographs showed the spherical nanocapsule with continuous intact shell.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP9003218 Poly(methyl acrylate) solution Poly(methyl acrylate) solution 9003-21-8 Price
qrcode