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Polymorphism of Doxazosin Mesylate

Young-Taek Sohn, Yoon-Hee Lee

Arch Pharm Res. 2005 Jun;28(6):730-5.

PMID: 16042084

Abstract:

Nine polymorphic modifications of doxazosin mesylate have been obtained by recrystallization in organic solvents under variable conditions. Different polymorphs of doxazosin mesylate were characterized by powder X-ray crystallography diffractometry (PXRD), differential scanning calorimetry (DSC), and thermogravimetric analysis (TG). Transformation of Form 1 and Form 2 was not occurred in three relative humidities (0%, 51%, and 99%) at 20 +/- 0.5 for 30 days.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP77883433 Doxazosin mesylate Doxazosin mesylate 77883-43-3 Price
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