Home
Resources
Publications
Portal and Vena Caval Plasma Methionine Concentrations in Young Pigs Administered L-methionine, N-acetyl-L-methionine and N-acetyl-D-methionine

Portal and Vena Caval Plasma Methionine Concentrations in Young Pigs Administered L-methionine, N-acetyl-L-methionine and N-acetyl-D-methionine

T T Daabees, D W Andersen, W L Zike, L J Filer Jr, L D Stegink

J Nutr. 1984 Sep;114(9):1541-7.

PMID: 6470816

Abstract:

N-Acyl-methionine derivatives have been proposed as replacements for methionine in supplementing food products low in this amino acid. We studied the effects of N-acetyl-L-methionine, N-acetyl-D-methionine and L-methionine loads (2 mmol/kg body weight) on portal and vena caval plasma amino acid concentrations in young pigs (n = 4). L-Methionine loading significantly increased mean (+/- SD) portal and vena caval plasma methionine concentrations from baseline values of 6.44 +/- 1.03 and 6.63 +/- 0.99 mumol/100 ml, respectively, to mean peak values of 340 +/- 75.0 and 265 +/- 49.8 mumol/100 ml, respectively. N-Acetyl-L-methionine loading increased mean peak portal and vena caval plasma methionine concentrations to 291 +/- 85 and 220 +/- 51.6 mumol/100 ml, respectively. N-Acetyl-L-methionine could not be detected in either portal or vena caval plasma. In contrast, N-acetyl-D-methionine loading produced only a small rise in mean peak portal and vena caval plasma methionine concentrations (13.0 +/- 4.31 and 8.62 +/- 1.71 mumol/100 ml, respectively). Concentrations of N-acetyl-D-methionine increased from baseline values of 0 mumol/100 ml to mean peak values of 251 +/- 32.0 and 234 +/- 72.3 mumol/100 ml, respectively, in portal and vena caval plasma. These data explain the poor utilization of N-acetyl-D-methionine as a methionine source.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP1115475	N-Acetyl-D,L-Methionine		1115-47-5	Price

As a specialist in analytical chemical Products, Alfa Chemistry offers consumers a wealth of raw materials and a full range of technologies and services.

QUICK LINKS

HEADQUARTERS

Tel:

Fax:

Email: