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Possible Role of Nitric Oxide in Transmitting Information From Vasodilator Nerve to Cerebroarterial Muscle

N Toda, T Okamura

Biochem Biophys Res Commun. 1990 Jul 16;170(1):308-13.

PMID: 2164808

Abstract:

Treatment with L-NG-monomethyl arginine (L-NMMA), an inhibitor of nitric oxide (NO) synthesis from L-arginine, suppressed the relaxant response of dog cerebral artery strips to transmural electrical stimulation and nicotine, as did oxyhemoglobin. The inhibition by L-NMMA was reversed or prevented by L-, but not D-, arginine. It is concluded that NO or an NO-related compound may play a crucial role in transmitting information from excited vasodilator nerves to cerebroarterial smooth muscle.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
ALP532127 Nicotine Related Compound D Nicotine Related Compound D 532-12-7 (free base) Price
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