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Potassium Salt of Fullerenylpenta-N-Dihydroxytyrosine Effects on Type 2 Diabetes Mellitus Therapeutic Targets

Yu V Soldatova, R A Kotelnikova, A V Zhilenkov, I I Faingold, P A Troshin, M A Kozlova, D A Areshidze, S M Aldoshin

Dokl Biochem Biophys. 2019 Sep;488(1):320-323.

PMID: 31768851

Abstract:

It was shown for the first time that pentaamino acid derivative of fullerene C60 (potassium salt of fullerenylpenta-N-dihydroxytyrosine) affects three targets of type 2 diabetes mellitus. It competitively inhibits the enzymes aldose reductase and sorbitol dehydrogenase and also has an antiglycation effect on bovine serum albumin. The inhibition constants for these enzymes were calculated.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
LS7931549 2-hydroxyphenyltrifluoroborate potassium salt 2-hydroxyphenyltrifluoroborate potassium salt Price
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