Home
Resources
Publications
Preparation and Characterization of Temperature-Responsive poly(N-isopropylacrylamide-co-N,N'-methylenebisacrylamide) Monolith for HPLC

Preparation and Characterization of Temperature-Responsive poly(N-isopropylacrylamide-co-N,N'-methylenebisacrylamide) Monolith for HPLC

Mingquan Liu, Haiyan Liu, Yankun Liu, Ligai Bai, Gengliang Yang, Chunliu Yang, Jia Cheng

J Chromatogr A. 2011 Jan 14;1218(2):286-92.

PMID: 21146172

Abstract:

A temperature-responsive poly(N-isopropylacrylamide-co-N,N'-methylenebisacrylamide) [poly(NIPAAm-co-BIS)] monolith was prepared via a free-radical polymerization technique using an aqueous redox initiator in solution at -12°C. The effect of the % T (total monomer concentration/100 mL) and % C (cross-linker concentration/100 mL) on the visual form was investigated. The effect of the porogen on the pore structure was characterized by SEM. Under the optimum condition, the monolith for HPLC was successfully prepared and its mechanical strength and permeability have been studied. Furthermore, a temperature-dependent resolution of aromatic ketones was achieved using only water as mobile phase. The increasing interaction between solutes and the monolith was observed when temperature increased. The theoretical plate number of every analyte was more than 10(4).

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP110269	N,N′-Methylenebisacrylamide solution		110-26-9	Price

As a specialist in analytical chemical Products, Alfa Chemistry offers consumers a wealth of raw materials and a full range of technologies and services.

QUICK LINKS

HEADQUARTERS

Tel:

Fax:

Email: