Home
Resources
Publications
Preparation of dehydro-L-ascorbic Acid Dimer by Air Oxidation of L-ascorbic Acid in the Presence of Catalytic Amounts of copper(II) Acetate and Pyridine

Preparation of dehydro-L-ascorbic Acid Dimer by Air Oxidation of L-ascorbic Acid in the Presence of Catalytic Amounts of copper(II) Acetate and Pyridine

Eleftheria K Koliou, Panayiotis V Ioannou

Carbohydr Res. 2005 Feb 7;340(2):315-8.

PMID: 15639252

Abstract:

The catalytic system Cu(AcO)2-pyridine 1:4 mol% in methanol, slowly catalyses the air oxidation of ascorbic acid to the 2-methyl hemi-ketal of dehydroascorbic acid 5, and hydrogen peroxide. However, with Cu(AcO)2-pyridine 3:4 mol% the air oxidation is quite fast and no hydrogen peroxide is present at the end of the reaction. Removal of the catalyst and refluxing the foamy 5 in MeCN gives the oxidized, dimeric, dehydroascorbic acid in very good yields (approximately 70%) contaminated by approximately 1-2% MeCN.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP72691259	Dehydro-L-(+)-ascorbic acid dimer		72691-25-9	Price

As a specialist in analytical chemical Products, Alfa Chemistry offers consumers a wealth of raw materials and a full range of technologies and services.

QUICK LINKS

HEADQUARTERS

Tel:

Fax:

Email: