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Preparation of Monovalent Succinyl-Concanavalin A and Its Mitogenic Activity

M Beppu, T Terao, T Osawa

J Biochem. 1976 May;79(5):1113-7.

PMID: 956138

Abstract:

Monovalent succinyl-concanavalin A was prepared by photoaffinity labeling of succinyl-concanavalin A with p-azidophenyl a-D-mannopyranoside. This concanavalin A derivate showed a weak but definite mitogenic acitivity against mouse splenic lymphocytes and human peripheral lymphocytes, suggesting that direct receptor cross-linkage on the cell surface is not an obligatory prerequisite for the activation of lymphocytes.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
IAR42417959 Succinyl-Concanavalin A Succinyl-Concanavalin A Price
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