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Production of cis-11-eicosenoic Acid by Mortierella Fungi

Production of cis-11-eicosenoic Acid by Mortierella Fungi

H Kikukawa, E Sakuradani, Y Nishibaba, T Okuda, A Ando, J Shima, S Shimizu, J Ogawa

J Appl Microbiol. 2015 Mar;118(3):641-7.

PMID: 25495454

Abstract:

Aim:
To find cis-11-eicosenoic acid (20:1ω9, EA)-producing micro-organisms.
Methods and results:
We found EA-producing fungi by screening about 300 fungal strains and identified a major fatty acid accumulated in the Mortierella fungi as EA by means of GC-MS analysis. In particular, Mortierella chlamydospora CBS 529.75 produced a high amount of EA (36.3 mg g(-1) of dried cells) on cultivation at 28°C for 4 days and then at 12°C for 3 days. In the result of lipid analysis, most of the EA was a component of triacylglycerols, not phospholipids.
Conclusion:
We found that M. chlamydospora CBS 529.75 was the best producer for the microbial production of EA.
Significance and impact of the study:
EA is beneficial as a raw material for medical supplies and a moisturizing component of cosmetic creams. This is the first report of microbial production of EA.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP5561999	cis-11-Eicosenoic acid		5561-99-9	Price

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