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Properties and Clinical Development of a Novel Coating Technology: The Poly[bis(trifluoroethoxy)phosphazene]

Properties and Clinical Development of a Novel Coating Technology: The Poly[bis(trifluoroethoxy)phosphazene]

Davide Capodanno, Corrado Tamburino

Recent Pat Drug Deliv Formul. 2010 Jan;4(1):18-22.

PMID: 19939221

Abstract:

Ultrapure poly[bis(trifluoroethoxy)phosphazene] is a novel biocompatible, anti-inflammatory, antithrombogenic polymer which has the potential to cover stent devices without elution of a cell cycle inhibiting drug. The properties of polyphosphazene are likely to extend its use to a broad array of promising applications. This article reviews the features of the polymer and some recent patents related to use of poly[bis(trifluoroethoxy)phosphazene] in coating, its relevance as compared to other polymers, current evidence on pre-clinical and clinical performance, and future perspectives.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
LS775301	Poly(bis(1,4-dioxapentyl)phosphazene)			Price

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