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Prospective Comparison of the Fluorescein-Dilaurate Test With the Secretin-Cholecystokinin Test for Pancreatic Exocrine Function

Prospective Comparison of the Fluorescein-Dilaurate Test With the Secretin-Cholecystokinin Test for Pancreatic Exocrine Function

E J Boyd, J G Cumming, A Cuschieri, R A Wood, K G Wormsley

J Clin Pathol. 1982 Nov;35(11):1240-3.

PMID: 7142432

Abstract:

In a prospective study of 60 patients undergoing investigation for possible exocrine pancreatic disease the fluorescein-dilaurate test was compared with the secretin-cholecystokinin (CCK) test. Forty one patients had a normal response to secretin-CCK, 14 patients had abnormal responses and in five patients the results were equivocal. Taking the secretin-CCK test as the diagnostic criterion, the fluorescein-dilaurate test had a sensitivity of 100% and a negative predictive value of 100%. There was a 54% false-positive rate. The fluorescein-dilaurate test is easy to perform and is a useful screening test for pancreatic exocrine insufficiency.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP7308909	Fluorescein dilaurate		7308-90-9	Price

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