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Psychometric Performance of the CAMPHOR and SF-36 in Pulmonary Hypertension

Psychometric Performance of the CAMPHOR and SF-36 in Pulmonary Hypertension

James Twiss, Stephen McKenna, Louise Ganderton, Sue Jenkins, Mitra Ben-L'amri, Kevin Gain, Robin Fowler, Eli Gabbay

BMC Pulm Med. 2013 Jul 12;13:45.

PMID: 23844640

Abstract:

Background:
The Cambridge Pulmonary Hypertension Outcome Review (CAMPHOR) and the Medical Outcomes Study Short Form 36 (SF-36) are widely used to assess patient-reported outcome in individuals with pulmonary hypertension (PH). The aim of the study was to compare the psychometric properties of the two measures.
Methods:
Participants were recruited from specialist PH centres in Australia and New Zealand. Participants completed the CAMPHOR and SF-36 at two time points two weeks apart. The SF-36 is a generic health status questionnaire consisting of 36 items split into 8 sections. The CAMPHOR is a PH-specific measure consisting of 3 scales; symptoms, activity limitations and needs-based QoL. The questionnaires were assessed for distributional properties (floor and ceiling effects), internal consistency (Cronbach's alpha), test-retest reliability and construct validity (scores by World Health Organisation functional classification).
Results:
The sample comprised 65 participants (mean (SD) age = 57.2 (14.5) years; n(%) male = 14 (21.5%)). Most of the patients were in WHO class 2 (27.7%) and 3 (61.5%). High ceiling effects were observed for the SF-36 bodily pain, social functioning and role emotional domains. Test-retest reliability was poor for six of the eight SF-36 domains, indicating high levels of random measurement error. Three of the SF-36 domains did not distinguish between WHO classes. In contrast, all CAMPHOR scales exhibited good distributional properties, test retest reliability and distinguished between WHO functional classes.
Conclusions:
The CAMPHOR exhibited superior psychometric properties, compared with the SF-36, in the assessment of PH patient-reported outcome.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP464482	(−)-Camphor		464-48-2	Price
AP464493-A	Camphor		464-49-3	Price

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