Home
Resources
Publications
Purification and Characterization of Bioactive Peptides From Skin Extracts of Rana Esculenta

Purification and Characterization of Bioactive Peptides From Skin Extracts of Rana Esculenta

M Simmaco, D De Biase, C Severini, M Aita, G F Erspamer, D Barra, F Bossa

Biochim Biophys Acta. 1990 Mar 26;1033(3):318-23.

PMID: 2317508

Abstract:

The peptide fraction extracted by methanol from the skin of Rana esculenta, a species widely distributed in Western Europe, was investigated. The pharmacological activity found in the extract is attributable to the presence of authentic bradykinin, together with a shorter, partially active version of this molecule, des-Arg9-bradykinin. Also the bradykinin fragment 1-7 has been isolated, but it was inactive in our bioassay system. Moreover, a family of hydrophobic peptides has been purified and characterized, which appeared devoid of pharmacological activities when tested on smooth muscle preparations, but were provided with hemolytic activities.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP23815874	Bradykinin Fragment 1-7		23815-87-4	Price

As a specialist in analytical chemical Products, Alfa Chemistry offers consumers a wealth of raw materials and a full range of technologies and services.

QUICK LINKS

HEADQUARTERS

Tel:

Fax:

Email: