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Pyridine Derivatives, Especially 2,6-di-tert-butylpyridine, Labeled With nitrogen-15

Dan Fărcaşiu, Marta Lezcano

J Labelled Comp Radiopharm. 2013 Oct;56(12):637-8.

PMID: 24285241

Abstract:

Pyridine derivatives labeled with (15) N can be prepared by the reaction of the corresponding pyrylium salts with (15) NH4 Cl in close to a stoichiometric ratio, in a sodium acetate-acetic acid buffer. In particular, the reaction of 2,6-di-tert-butylpyrylium perchlorate gave 2,6-di-tert-butylpyridine with a conversion of 95%. The compound is valuable for studies of acid-base interactions on solid acid catalysts by (15) N nuclear magnetic resonance.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP39466621 Ammonium-15N chloride Ammonium-15N chloride 39466-62-1 Price
AP86451356 Ammonium-15N acetate Ammonium-15N acetate 86451-35-6 Price
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