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Qualitative and Quantitative Analysis of the Product and By-Products From Transesterification Between Phenol and Dimethyl Carbonate

Tao Liu, Jing Hu, Li Yong, Gang Zhang, Yi Zhang, Tong Chen, Gongying Wang

J Anal Methods Chem. 2019 Mar 6;2019:7632520.

PMID: 30984443

Abstract:

By-products (phenyl salicylate, phenyl 4-hydroxybenzoate, and xanthone) from transesterification between phenol and dimethyl carbonate (DMC) were qualitatively analyzed by gas chromatography-mass spectrometry, and a gas chromatographic method with directed injection for simultaneous quantitative analysis of the product (DPC) and by-products of the transesterification has been established. Based on the results of qualitative and quantitative analyses, the mechanism of the by-products generation was preliminarily deduced. The sample for quantitative analysis was directly diluted in acetone, and related compounds were separated on an HP-5 capillary column and detected by a hydrogen flame ionization detector (FID). The product and by-products were well separated, the correlation coefficients (r) within the concentration range of 1.0 μg/mL-100 μg/mL were ≥0.9997, the relative standard deviations were between 0.5% and 4.4%, spiked recoveries were between 91.5% and 105.6%, and detection limits were between 0.11 and 0.18 μg/mL. The established method is simple, rapid, accurate, sensitive, and highly specific. It is suitable for simultaneous qualitative and quantitative analyses of the product and by-products of transesterification between phenol and DMC.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP17696627 Phenyl 4-hydroxybenzoate Phenyl 4-hydroxybenzoate 17696-62-7 Price
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