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Quantification of Mouse Lung Elastin During Prenatal Development

Paula Rodrigues, Carlos Gonçalves, Ana Honório, José Barros, Vasco Bairos

Open Respir Med J. 2008;2:46-51.

PMID: 19365535

Abstract:

Elastic fibres play a crucial function during the process of lung alveolisation. During the perinatal period, any changes in the elastogenic process during foetal development may result in permanent lifetime defects. In pre-natal life, well-developed pulmonary elastic fibres should favor the pre-natal maturation of the lung and an enhanced alveolisation, which in many species, such as humans begins only after birth. The authors present a quantitative study by image analysis and by high-pressure liquid chromatography (HPLC) of the mouse lungs' elastic fibre content from the 15th till the 19th gestational day.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP9007583-C Elastin from mouse lung Elastin from mouse lung 9007-58-3 Price
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