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Quinine and the ABCs of Long QT: A Patient's Misfortune With Arthritis, (Alcoholic) Beverages, and Cramps

Elyce T Sheehan, Jarrod D Frizzell, Jude Gabaldon, Michael B West

J Gen Intern Med. 2016 Oct;31(10):1254-7.

PMID: 27173501

Abstract:

A 91-year-old woman presented to the emergency department by ambulance after her family found her minimally responsive. Telemetry monitoring demonstrated episodes of non-sustained polymorphic ventricular tachycardia (PMVT) associated with significantly prolonged repolarization. Her medical history revealed that she was taking quinine or a derivative in three different forms: hydroxychloroquine, quinine sulfate (for leg cramps), and her gin mixed with tonic water (containing quinine). The present case is illustrative of classic etiologies and findings of acquired long QT syndrome, and serves as an important reminder for providers to take a complete medication history, including use of duplicative and alternative medicines and type of alcohol consumption.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP207671441 Quinine sulfate Quinine sulfate 207671-44-1 Price
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