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Rapid Identification of Candida Albicans Using 4-methylumbelliferyl N-acetyl-beta-galactosaminide

Rapid Identification of Candida Albicans Using 4-methylumbelliferyl N-acetyl-beta-galactosaminide

M T Dalton, D J Haldane, J MacDonald

Diagn Microbiol Infect Dis. Nov-Dec 1989;12(6):521-3.

PMID: 2696622

Abstract:

Rapid identification of Candida albicans is performed mainly by the germ-tube test. However, recent reports have suggested that up to 5% of C. albicans species can give false negative results. We describe the use of 4-Methylumbelliferyl N-acetyl-beta-D-galactosaminide (4-MAG) conjugate as an alternative to the germ-tube test. Our results indicate that, in comparison to the germ-tube test, the 4-MAG test has a sensitivity of 100% and a specificity of 92%. Candida tropicalis can give false-positive results, and that a further screening test is required to identify this species. Problems reading end-points were not encountered.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP36476296	4-Methylumbelliferyl N-acetyl-β-D-galactosaminide		36476-29-6	Price

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