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Rhapontigenin Converted From Rhapontin Purified From Rheum Undulatum Enhances the Inhibition of Melanin Synthesis

Hyun-Sun Lee, Jeong-Keun Kim, Keun-Tae Park, Young-Hee Lim

Biosci Biotechnol Biochem. 2012;76(12):2307-9.

PMID: 23221688

Abstract:

Rhapontigenin was produced from rhapontin isolated from a methanol extract of Rheum undulatum roots by enzymatic transformation. Rhapontin and rhapontigenin exhibited dose-dependent inhibition of tyrosinase activity and melanin synthesis in B16F10 melanoma cells, but the inhibitory activity of rhapontigenin was greater than that of rhapontin. Thus the bioconversion of rhapontin enhanced its ability to inhibit cellular tyrosinase activity and melanin synthesis.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP155588-B Rhapontin Rhapontin 155-58-8 Price
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