0

Rhodium-catalyzed Annulation Reactions of 2-cyanophenylboronic Acid With Alkynes and Strained Alkenes

Tomoya Miura, Masahiro Murakami

Org Lett. 2005 Jul 21;7(15):3339-41.

PMID: 16018655

Abstract:

[reaction: see text]. A new [3 + 2] annulation reaction was developed in which 2-cyanophenylboronic acid reacted as a three-carbon component with alkynes or alkenes to afford substituted indenones or indanones. The use of an alkynoate even produced benzotropone, a formal [3 + 2 + 2] adduct. The cyclic skeletons were constructed by intramolecular nucleophilic addition of an intermediate organorhodium(I) species to a cyano group.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP138642623 2-Cyanophenylboronic acid 2-Cyanophenylboronic acid 138642-62-3 Price
qrcode