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Rhodium-catalyzed Cycloaddition of 1,6-enynes With 2-bromophenylboronic Acids: Synthesis of a Multi-Substituted Dihydronaphthalene Scaffold

Xianjie Fang, Chaolong Li, Xiaofeng Tong

Chem Commun (Camb). 2009 Sep 21;(35):5311-3.

PMID: 19707656

Abstract:

A formal [2 + 2 + 2] cycloaddition of a 1,6-enyne with 2-bromophenylboronic acid has been realized to construct a multi-substituted dihydronaphthalene scaffold, in which the direct reductive elimination mechanism of aryl-Rh(iii)-C(sp(3)) species has been established to form an aryl-C(sp(3)) bond.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP244205401 2-Bromophenylboronic acid 2-Bromophenylboronic acid 244205-40-1 Price
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