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Rhodium(III)-Catalyzed C-H Alkynylation of N-Methylsulfoximines

Tao Wang, Yi-Ning Wang, Rui Wang, Xi-Sheng Wang

Chem Asian J. 2018 Sep 4;13(17):2449-2452.

PMID: 29978579

Abstract:

A rhodium(III)-catalyzed direct C-H alkynylation of a wide range of N-methylsulfoximines with (bromoethynyl)triisopropylsilane has been developed. This protocol is compatible with both (S,S)-diaryl sulfoximines and (S,S)-alkyl aryl sulfoximines, and shows mild conditions, and good functional group tolerance. The synthetic utility of this method has been demonstrated by subsequent various transformations of the products.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP17877235 Triisopropylsilanol Triisopropylsilanol 17877-23-5 Price
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