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Safety Evaluation of Lipase G From Penicillium Camembertii

Safety Evaluation of Lipase G From Penicillium Camembertii

M Kondo, T Ogawa, Y Matsubara, A Mizutani, S Murata, M Kitagawa

Food Chem Toxicol. 1994 Aug;32(8):685-96.

PMID: 8070733

Abstract:

Lipase G, a partial glycerides eliminating enzyme produced by Penicillium camembertii, was subjected to safety evaluation studies to establish its safety when used as a processing aid in the food industry. The toxicological studies on the enzyme included a 90-day gavage study with rats, a mutagenicity study using bacteria, and a pathogenicity study using mice. The no-adverse-effect level from the 90-day gavage toxicity study was 2000 mg/kg body weight/day for rats. There was no evidence of mutagenic potential. The micro-organism was evaluated for pathogenicity using mice and classified as a non-pathogen. Results indicate that the production and use of lipase G may be regarded as safe for the enzyme production worker and the consumer.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
IAR42416027	Amano Lipase G from Penicillium camemberti			Price

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