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Safety of a Preservative System Containing 1,2-hexanediol and Caprylyl Glycol

Stanley B Levy, Anthony M Dulichan, Michael Helman

Cutan Ocul Toxicol. 2009;28(1):23-4.

PMID: 19514921

Abstract:

To study the potential for delayed Type IV dermal sensitivity of a new preservative system containing 1,2-hexanediol and caprylyl glycol, 200-subject repeat insult patch tests were performed with a 15% mixture of 1,2-hexanediol and caprylyl glycol (equal parts of the 2 ingredients) in carbomer gel and a cosmetic formulation at an actual use concentration. No delayed Type IV hypersensitivity reactions were observed.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP627861 1,2-Dioctanoylethylene glycol 1,2-Dioctanoylethylene glycol 627-86-1 Price
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