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Selected-control Fabrication of Multifunctional Fluorescent-Magnetic Core-Shell and Yolk-Shell Hybrid Nanostructures

Selected-control Fabrication of Multifunctional Fluorescent-Magnetic Core-Shell and Yolk-Shell Hybrid Nanostructures

Haiyan Liu, Tingting Wang, Lingyu Zhang, Lu Li, Y Andrew Wang, Chungang Wang, Zhongmin Su

Chemistry. 2012 Mar 19;18(12):3745-52.

PMID: 22328547

Abstract:

The selected-control preparation of uniform core-shell and yolk-shell architectures, which combine the multiple functions of a superparamagnetic iron oxide (SPIO) core and europium-doped yttrium oxide (Y(2)O(3):Eu) shell in a single material with tunable fluorescence and magnetic properties, has been successfully achieved by controlling the heat-treatment conditions. Furthermore, the shell thickness and interior cavity of SPIO@Y(2)O(3):Eu core-shell and yolk-shell nanostructures can be precisely tuned. Importantly, as-prepared SPIO@Y(2)O(3):Eu yolk-shell nanocapsules (NCs) modified with amino groups as cancer-cell fluorescence imaging agents are also demonstrated. To the best of our knowledge, this is the first report on the selected-control fabrication of uniform SPIO@Y(2)O(3):Eu core-shell nanoparticles and yolk-shell NCs. The combined magnetic manipulation and optical monitoring of magnetic-fluorescent SPIO@Y(2)O(3):Eu yolk-shell NCs will open up many exciting opportunities in dual imaging for targeted delivery and thermal therapy.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP68585820	Yttrium oxide, europium doped		68585-82-0	Price

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