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Selective Synthesis of 2,4-bis(O-methoxypolyethylene glycol)-6-chloro-s-triazine as a Protein Modifier

Selective Synthesis of 2,4-bis(O-methoxypolyethylene glycol)-6-chloro-s-triazine as a Protein Modifier

K Ono, Y Kai, H Maeda, F Samizo, K Sakurai, H Nishimura, Y Inada

J Biomater Sci Polym Ed. 1991;2(1):61-5.

PMID: 1863578

Abstract:

2,4-Bis(O-methoxypolyethylene glycol)-6-chloro-s-triazine, a protein modifier with two polyethylene glycol chains (activated PEG2) was synthesized from monomethoxypolyethylene glycol and cyanuric chloride using zinc oxide as a catalyst by the improved method of a previous study (Matsushima et al., Chem. Lett. 7, 773, 1980). The product was identified as activated PEG2 without contamination of by-products with chromatographic and structural analysis.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
IAR42411380	Methoxypolyethylene glycol activated with cyanuric chloride			Price

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