Home
Resources
Publications
Separating the Isomers--Efficient Synthesis of the N-hydroxysuccinimide Esters of 5 and 6-carboxyfluorescein Diacetate and 5 and 6-carboxyrhodamine B

Separating the Isomers--Efficient Synthesis of the N-hydroxysuccinimide Esters of 5 and 6-carboxyfluorescein Diacetate and 5 and 6-carboxyrhodamine B

Aurélie Brunet, Tashfeen Aslam, Mark Bradley

Bioorg Med Chem Lett. 2014 Jul 15;24(14):3186-8.

PMID: 24856065

Abstract:

Diacetate protection of 5 and 6-carboxyfluorescein followed by synthesis of the N-hydroxysuccinimide esters allowed ready separation of the two isomers on a multi-gram scale. The 5 and 6-carboxyrhodamine B N-hydroxysuccinimide esters were also readily synthesised and separated.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP3348036	6-Carboxyfluorescein diacetate		3348-03-6	Price

As a specialist in analytical chemical Products, Alfa Chemistry offers consumers a wealth of raw materials and a full range of technologies and services.

QUICK LINKS

HEADQUARTERS

Tel:

Fax:

Email: