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Sesquiterpenoids From the Seeds of Sarcandra Glabra and the Potential Anti-Inflammatory Effects

Saimijiang Yaermaimaiti, Peng Wang, Jun Luo, Rui-Jun Li, Ling-Yi Kong

Fitoterapia. 2016 Jun;111:7-11.

PMID: 27050720

Abstract:

Five new sesquiterpenoids, including two linderanes (1-2) and three eudesmanes (3-5) were isolated from the seeds of Sarcandra glabra. Their structures and relative configurations were established by spectroscopic data analysis. 1 was a rare linderane derivative having an 18-membered triester ring which is a common characteristic in linderane dimers. Compounds 1-5 were investigated for their inhibitory effects on NO production in LPS-induced macrophages and 1 showed moderate bioactivity.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP13476250 Linderane Linderane 13476-25-0 Price
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