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Simple and Short Synthesis of trans-(R)-nerolidol, a Pheromone Component of Fruit Spotting Bug

C Le Thanh, Kamlesh R Chauhan

Nat Prod Commun. 2014 Mar;9(3):297-8.

PMID: 24689198

Abstract:

A three-step synthesis of enantiomerically pure (R) and (S)-trans nerolidol from commercially available E,E-fanesol is described. Trans nerolidol is an abundant sesquiterpene in many plant species, almost enantiomerically pure; however, the configuration of chirality is S. There is no natural resource for R-trans nerolidol, which has recently been identified as a pheromone component of the fruit spotting bug Amblypelta lutescens. The simple syntheses reported here will make enantiomerically pure R- and S-trans nerolidol and homologues available for further research and ultimately for use in integrated pest management strategies comprising pheromones.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP40716663 trans-Nerolidol trans-Nerolidol 40716-66-3 Price
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