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Simple Enzymatic Screening Assay for Ethylene Glycol (ethane-1,2-diol) in Serum

P Hansson, P Masson

Clin Chim Acta. 1989 Jun 15;182(1):95-101.

PMID: 2752583

Abstract:

We present a novel method for the analysis of ethylene glycol (ethane-1,2-diol) in serum. This method employs the ability of glycerol dehydrogenase (EC 1.1.1.6) to oxidize ethylene glycol. Two measurements, five and 30 min after addition of enzyme, are used to circumvent interferences from endogenous glycerol and from propylene glycol (propane-1,2-diol). Ethanol does not interfere in the assay. The method requires commonly available equipment only, making it suitable for all emergency laboratories.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP627861 1,2-Dioctanoylethylene glycol 1,2-Dioctanoylethylene glycol 627-86-1 Price
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