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Simultaneous High-Performance Liquid Chromatographic Determination of Antazoline Phosphate and Tetrahydrozoline Hydrochloride in Ophthalmic Solution

G Puglisi, S Sciuto, R Chillemi, S Mangiafico

J Chromatogr. 1986 Nov 7;369(1):165-70.

PMID: 3793827

Abstract:

A method for the determination of 2-[(N-phenyl)benzylaminomethyl]-2-imidazoline X H3PO4 (antazoline phosphate) and 2-(1,2,3,4-tetrahydro-1-naphthyl)-2-imidazoline X HCl (tetrahydrozoline hydrochloride) in ophthalmic solution is described. The pharmaceutical preparation is analysed directly by reversed-phase ion-pair high-performance liquid chromatography and the method is very rapid, selective and simple.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP522485-A Tetrahydrozoline hydrochloride Tetrahydrozoline hydrochloride 522-48-5 Price
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