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Single-walled Carbon Nanotubes as Near-Infrared Optical Biosensors for Life Sciences and Biomedicine

Single-walled Carbon Nanotubes as Near-Infrared Optical Biosensors for Life Sciences and Biomedicine

Astha Jain, Aida Homayoun, Christopher W Bannister, Kyungsuk Yum

Biotechnol J. 2015 Mar;10(3):447-59.

PMID: 25676253

Abstract:

Single-walled carbon nanotubes that emit photostable near-infrared fluorescence have emerged as near-infrared optical biosensors for life sciences and biomedicine. Since the discovery of their near-infrared fluorescence, researchers have engineered single-walled carbon nanotubes to function as an optical biosensor that selectively modulates its fluorescence upon binding of target molecules. Here we review the recent advances in the single-walled carbon nanotube-based optical sensing technology for life sciences and biomedicine. We discuss the structure and optical properties of single-walled carbon nanotubes, the mechanisms for molecular recognition and signal transduction in single-walled carbon nanotube complexes, and the recent development of various single-walled carbon nanotube-based optical biosensors. We also discuss the opportunities and challenges to translate this emerging technology into biomedical research and clinical use, including the biological safety of single-walled carbon nanotubes. The advances in single-walled carbon nanotube-based near-infrared optical sensing technology open up a new avenue for in vitro and in vivo biosensing with high sensitivity and high spatial resolution, beneficial for many areas of life sciences and biomedicine.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP308068566-B	Carbon nanotube, single-walled		308068-56-6	Price

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