0

Small Molecule Targeting miR-34a for Cancer Therapy

Zhangang Xiao, Yangchao Chen

Mol Cell Oncol. 2015 Feb 24;2(1):e977160.

PMID: 27308410

Abstract:

miR-34a functions as a tumor suppressor in many cancers. In a recent issue of Cancer Research, we describe a small molecule, Rubone, with strong anticancer activity. Rubone selectively restored miR-34a expression in hepatocellular carcinoma cells in which miR-34a was silenced. Restoration of miR-34a by Rubone represents a promising therapeutic approach against cancer.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP73694152 Rubone Rubone 73694-15-2 Price
qrcode