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Sodium Saccharin Can Be More Acceptable to Rats Than Pure Saccharin

Sodium Saccharin Can Be More Acceptable to Rats Than Pure Saccharin

Simone Rehn, Takuya Onuma, Kieron B Rooney, Robert A Boakes

Behav Processes. 2018 Dec;157:188-191.

PMID: 30267767

Abstract:

The artificial sweetener saccharin is available in several forms, including pure saccharin (S) and saccharin sodium salt hydrate (SSSH). Acceptance and preference relative to 2% sucrose for these two forms was assessed using both older female and young male rats. At the higher of two concentrations, ∼0.4%, SSSH was more acceptable and more greatly preferred over 2% sucrose than was a similar concentration of S, whereas little difference between the two forms was detected at the lower concentration, ∼0.1%. These results indicate the importance for researchers of care in choosing and reporting the form of saccharin they use.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
IAR42411261	2-Keto-3-methylbutyric acid-3-d sodium salt hydrate			Price

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